St. Catherine of Siena Medical Center Share: HOSPITALSHEALTH RELATED St. Catherine of Siena Medical Center Visit Website 50 Route 25a Smithtown, NY 11787 (631) 862-3523 About Map About 296 bed not-for-profit community hospital, a 240 bed nursing and rehabilitation care center and a medical office building devoted to advanced health care in a compassionate environment. What's Nearby? Distance: 5 10 15 20 25 50 mi.